HDAC4 anticorps (AA 1049-1077)

N° du produit ABIN3031231

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC4 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour HDAC4 anticorps (AA 1049-1077) (ABIN3031231)

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-HDAC4 anticorps

Épitope: AA 1049-1077

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1049-1077 from the human protein was used as the immunogen for this HDAC4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the HDAC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the HDAC4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process