HES1 anticorps (C-Term)

N° du produit ABIN3031193

L’anticorps Lapin Polyclonal anti-HES1 a été validé pour WB et ELISA. Il convient pour détecter HES1 dans des échantillons de Humain.

Aperçu rapide pour HES1 anticorps (C-Term) (ABIN3031193)

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HES1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HES1 anticorps

Épitope: C-Term

Réactivité croisée (Details): Expected species reactivity: Bovine

Purification: Antigen affinity purified

Immunogène: This HES1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 259-293 amino acids from the C-terminal region of human HES1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the HES1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the HES1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur HES1

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Autre désignation: HES1

Sujet: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

UniProt: Q14469

Pathways: Réparation de l'ADN