HES1 anticorps (C-Term)
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- Antigène Voir toutes HES1 Anticorps
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HES1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée (Details)
- Expected species reactivity: Bovine
- Purification
- Antigen affinity purified
- Immunogène
- This HES1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 259-293 amino acids from the C-terminal region of human HES1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product HES1 Anticorps primaire
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- Indications d'application
- Titration of the HES1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the HES1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Autre désignation
- HES1 (HES1 Produits)
- Synonymes
- anticorps HES-1, anticorps HHL, anticorps HRY, anticorps bHLHb39, anticorps Hry, anticorps HAIRY1, anticorps c-hairy1A, anticorps Xhairy1, anticorps hairy1, anticorps hes1, anticorps Xhairy-1, anticorps Xlh1, anticorps hes family bHLH transcription factor 1, anticorps hairy and enhancer of split 1 (Drosophila), anticorps hes family bHLH transcription factor 4, anticorps hes family bHLH transcription factor 1 S homeolog, anticorps hes family bHLH transcription factor 1 L homeolog, anticorps HES1, anticorps Hes1, anticorps HES4, anticorps hes1.S, anticorps hes1.L
- Sujet
- Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
- UniProt
- Q14469
- Pathways
- Réparation de l'ADN
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