IL-13 anticorps (AA 118-146)

N° du produit ABIN3031449

Cet anticorps anti-IL-13 est un anticorps Lapin Polyclonal détectant IL-13 dans WB, ELISA, IHC et IF. Adapté pour Humain.

Aperçu rapide pour IL-13 anticorps (AA 118-146) (ABIN3031449)

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IL-13 anticorps

Épitope: AA 118-146

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IL-13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur IL-13

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Autre désignation: IL-13

Sujet: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

UniProt: P35225

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport