INSRR anticorps (AA 16-47)

N° du produit ABIN3029806

Cet anticorps Lapin Polyclonal détecte spécifiquement INSRR dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour INSRR anticorps (AA 16-47) (ABIN3029806)

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSRR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-INSRR anticorps

Épitope: AA 16-47

Purification: Purified

Immunogène: A portion of amino acids 16-47 from the human protein was used as the immunogen for this Insulin receptor-related antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Insulin receptor-related antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Insulin receptor-related antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur INSRR

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Autre désignation: Insulin Receptor-Related

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: P14616

Pathways: Signalisation RTK