IRAK2 anticorps (AA 549-581)

N° du produit ABIN3031493

Détail du produit anti-IRAK2 anticorps

Antigène: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Épitope: AA 549-581

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogène: A portion of amino acids 549-581 from the human protein was used as the immunogen for this IRAK2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the IRAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IRAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRAK2

Antigène: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Autre désignation: IRAK2 (IRAK2 Produits)

Synonymes: anticorps IRAK-2, anticorps 6330415L08Rik, anticorps AI649099, anticorps interleukin 1 receptor associated kinase 2, anticorps interleukin-1 receptor-associated kinase 2, anticorps IRAK2, anticorps Irak2

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

UniProt: O43187

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades