KEAP1 anticorps (AA 422-449)

N° du produit ABIN3031535

L’anticorps Souris Monoclonal anti-KEAP1 a été validé pour WB et ELISA. Il convient pour détecter KEAP1 dans des échantillons de Humain.

Aperçu rapide pour KEAP1 anticorps (AA 422-449) (ABIN3031535)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KEAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 297CT6-1-6

Détail du produit anti-KEAP1 anticorps

Épitope: AA 422-449

Réactivité croisée (Details): Expected species reactivity: Pig

Purification: Purified

Immunogène: A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.

Isotype: IgM kappa

Information d'application

Indications d'application: Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: KEAP1

Sujet: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

UniProt: Q14145

Pathways: Maintenance of Protein Location