LRP5 anticorps (AA 1538-1567)

N° du produit ABIN3031641

Cet anticorps anti-LRP5 est un anticorps Lapin Polyclonal détectant LRP5 dans WB, IHC et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour LRP5 anticorps (AA 1538-1567) (ABIN3031641)

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-LRP5 anticorps

Épitope: AA 1538-1567

Purification: Purified

Immunogène: A portion of amino acids 1538-1567 from the human protein was used as the immunogen for this LRP5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the LRP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LRP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur LRP5

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Autre désignation: LRP5

Sujet: Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.

UniProt: O75197

Pathways: Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation