LRP6 anticorps (AA 1531-1560)

N° du produit ABIN3028807

Cet anticorps Lapin Polyclonal détecte spécifiquement LRP6 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour LRP6 anticorps (AA 1531-1560) (ABIN3028807)

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-LRP6 anticorps

Épitope: AA 1531-1560

Purification: Purified

Immunogène: A portion of amino acids 1531-1560 from the human protein was used as the immunogen for this LRP6 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the LRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6

Sujet: LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation