MARCKS
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
RB04646
unconjugated
Indications d'application
Titration of the MARCKS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the MARCKS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
MARCKS
(Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
Autre désignation
MARCKS
Sujet
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.