MCM3 anticorps (AA 36-64)

N° du produit ABIN3031804

Cet anticorps Lapin Polyclonal détecte spécifiquement MCM3 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MCM3 anticorps (AA 36-64) (ABIN3031804)

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MCM3 anticorps

Épitope: AA 36-64

Réactivité croisée (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 36-64 from the human protein was used as the immunogen for this MCM3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MCM3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MCM3

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Autre désignation: MCM3

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].

UniProt: P25205

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA