MLH1 anticorps (AA 452-480)

N° du produit ABIN3031882

Cet anticorps Lapin Polyclonal détecte spécifiquement MLH1 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour MLH1 anticorps (AA 452-480) (ABIN3031882)

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-MLH1 anticorps

Épitope: AA 452-480

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MLH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MLH1

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Autre désignation: MLH1

Sujet: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

UniProt: P40692

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response