MMP2 anticorps (AA 303-331)

N° du produit ABIN3031729

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MMP2 anticorps (AA 303-331) (ABIN3031729)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP2 anticorps

Épitope: AA 303-331

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Chicken, Rabbit

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 303-331 from the human protein was used as the immunogen for this MMP2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P08253

Pathways: Activation of Innate immune Response