NLRP10 anticorps (AA 466-494)

N° du produit ABIN3032014

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP10 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NLRP10 anticorps (AA 466-494) (ABIN3032014)

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-NLRP10 anticorps

Épitope: AA 466-494

Fonction: NLRP10 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NLRP10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NLRP10

Sujet: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

UniProt: Q86W26

Pathways: Inflammasome