NLRP10 anticorps (AA 466-494)

N° du produit ABIN3032014

Détail du produit anti-NLRP10 anticorps

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Épitope: AA 466-494

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NLRP10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NLRP10 (NLRP10 Produits)

Synonymes: anticorps CLR11.1, anticorps NALP10, anticorps NOD8, anticorps PAN5, anticorps PYNOD, anticorps 6430548I20Rik, anticorps Nalp10, anticorps Napl10, anticorps Pynod, anticorps NLR family pyrin domain containing 10, anticorps NLR family, pyrin domain containing 10, anticorps NLRP10, anticorps Nlrp10

Sujet: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

UniProt: Q86W26

Pathways: Inflammasome