NOTCH4 anticorps (C-Term)

N° du produit ABIN3032033

L’anticorps Lapin Polyclonal anti-NOTCH4 a été validé pour WB et ELISA. Il convient pour détecter NOTCH4 dans des échantillons de Humain.

Aperçu rapide pour NOTCH4 anticorps (C-Term) (ABIN3032033)

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NOTCH4 anticorps

Épitope: C-Term

Purification: Antigen affinity purified

Immunogène: This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NOTCH4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NOTCH4

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Autre désignation: NOTCH4

Sujet: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

UniProt: Q99466

Pathways: Signalisation Notch