PAK3 anticorps (AA 218-247)

N° du produit ABIN3032142

Détail du produit anti-PAK3 anticorps

Antigène: PAK3

Épitope: AA 218-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogène: A portion of amino acids 218-247 from the human protein was used as the immunogen for this PAK3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PAK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PAK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PAK3

Antigène: PAK3

Autre désignation: PAK3 (PAK3 Produits)

Synonymes: anticorps CDKN1A, anticorps MRX30, anticorps MRX47, anticorps OPHN3, anticorps PAK3beta, anticorps bPAK, anticorps hPAK3, anticorps PAK-3, anticorps Pak65alpha, anticorps Pak65beta, anticorps Stk4, anticorps beta-PAK, anticorps XPak3, anticorps bpak, anticorps cdkn1a, anticorps mrx30, anticorps mrx47, anticorps ophn3, anticorps pak3, anticorps pak3-A, anticorps pak3beta, anticorps p21 (RAC1) activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3, anticorps p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog, anticorps PAK3, anticorps Pak3, anticorps pak3.L

Sujet: PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.

UniProt: O75914