PGK1 anticorps (AA 117-145)

N° du produit ABIN3032224

Cet anticorps Lapin Polyclonal détecte spécifiquement PGK1 dans WB, ELISA, IHC, IF et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour PGK1 anticorps (AA 117-145) (ABIN3032224)

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PGK1 anticorps

Épitope: AA 117-145

Réactivité croisée (Details): Expected species reactivity: Primate, Rat

Purification: Purified

Immunogène: A portion of amino acids 117-145 from the human protein was used as the immunogen for this PGK1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PGK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PGK1

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Autre désignation: PGK1

Sujet: Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process