TSC1 anticorps (pThr310)

N° du produit ABIN3029298

Cet anticorps anti-TSC1 est un anticorps Lapin Polyclonal détectant TSC1 dans DB et ELISA. Adapté pour Souris.

Aperçu rapide pour TSC1 anticorps (pThr310) (ABIN3029298)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Dot Blot (DB), ELISA

Détail du produit anti-TSC1 anticorps

Épitope: pThr310

Purification: Antigen affinity purified

Immunogène: This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT310 of mouse TSC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-TSC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

UniProt: Q9EP53

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation