PML anticorps (Sumoylation Site)
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- Antigène Voir toutes PML Anticorps
- PML (Promyelocytic Leukemia (PML))
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Épitope
- AA 470-499, Sumoylation Site
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PML est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 470-499 (sumoylation site) from the human protein was used as the immunogen for this PML antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PML Anticorps primaire
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anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML Reactivité: Humain WB, IF, ELISA, PLA Hôte: Souris Monoclonal 1D12 unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibodyPML Reactivité: Humain WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB2570 unconjugated
anti-Promyelocytic Leukemia (PML) (AA 300-600) antibodyPML Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (C-Term) antibodyPML Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Porc, Lapin, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 411-510) antibodyPML Reactivité: Humain WB, IF, ELISA Hôte: Souris Monoclonal 2B10 unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML Reactivité: Humain WB, IHC, IF, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 588-637) antibodyPML Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 59-239) antibodyPML Reactivité: Humain WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML Reactivité: Humain WB, IHC, IF, IC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Titration of the PML antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the PML antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- PML (Promyelocytic Leukemia (PML))
- Autre désignation
- PML (PML Produits)
- Synonymes
- anticorps MYL, anticorps PP8675, anticorps RNF71, anticorps TRIM19, anticorps 1200009E24Rik, anticorps AI661194, anticorps Trim19, anticorps RGD1562602, anticorps PML, anticorps promyelocytic leukemia, anticorps PML, anticorps Pml
- Sujet
- PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
- UniProt
- P29590
- Pathways
- Signalisation p53, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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