PRMT2 anticorps (AA 22-53)
Aperçu rapide pour PRMT2 anticorps (AA 22-53) (ABIN3032356)
Antigène
Voir toutes PRMT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 22-53
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Purification
- Purified
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Immunogène
- A portion of amino acids 22-53 from the human protein was used as the immunogen for this PRMT2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the PRMT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PRMT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
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Autre désignation
- PRMT2
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Sujet
- Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
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UniProt
- P55345
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding
Antigène
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