PUMA anticorps (AA 119-154)
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- Antigène Voir toutes PUMA (BBC3) Anticorps
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Épitope
- AA 119-154
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PUMA est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
- Purification
- Purified
- Immunogène
- A portion of amino acids 119-154 (BH3 domain) from the human protein was used as the immunogen for this Puma antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product BBC3 Anticorps primaire
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anti-BCL2 Binding Component 3 (BBC3) antibody
BBC3 Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibodyBBC3 Reactivité: Humain WB, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibodyBBC3 Reactivité: Humain, Rat, Porc WB, ELISA, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reactivité: Humain WB, FACS, IHC (p), IF Hôte: Lapin Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PE)BBC3 Reactivité: Humain WB, ICC, IF Hôte: Lapin Polyclonal PE
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PerCP)BBC3 Reactivité: Humain WB, ICC, IF Hôte: Lapin Polyclonal PerCP
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody (Biotin)BBC3 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal Biotin
anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibodyBBC3 Reactivité: Humain, Souris WB, FACS, IHC (p), IF, EIA Hôte: Lapin Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibodyBBC3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB33714 unconjugated
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- Indications d'application
- Titration of the Puma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the Puma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Autre désignation
- Puma (BBC3 Produits)
- Synonymes
- anticorps BBC3, anticorps Puma, anticorps JFY-1, anticorps JFY1, anticorps PUMA, anticorps PUMA/JFY1, anticorps BCL2 binding component 3, anticorps Bcl-2 binding component 3, anticorps BBC3, anticorps Bbc3, anticorps bbc3
- Sujet
- PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
- UniProt
- Q9BXH1
- Pathways
- Signalisation p53, Positive Regulation of Endopeptidase Activity
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