Recoverin anticorps (AA 169-200)
Aperçu rapide pour Recoverin anticorps (AA 169-200) (ABIN3032452)
Antigène
Voir toutes Recoverin (RCVRN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 169-200
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Fonction
- Recoverin Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 169-200 from the human protein was used as the immunogen for this Recoverin antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Recoverin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Recoverin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Recoverin (RCVRN)
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Autre désignation
- Recoverin
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Sujet
- Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.
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UniProt
- P35243
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Antigène
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