REST anticorps (AA 542-570)

N° du produit ABIN3028976

L’anticorps Lapin Polyclonal anti-REST a été validé pour WB et ELISA. Il convient pour détecter REST dans des échantillons de Humain.

Aperçu rapide pour REST anticorps (AA 542-570) (ABIN3028976)

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-REST anticorps

Épitope: AA 542-570

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 542-570 from the human protein was used as the immunogen for this REST antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the REST antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the REST antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: REST

Sujet: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity