RIPK3 anticorps (AA 1-30)
Aperçu rapide pour RIPK3 anticorps (AA 1-30) (ABIN3032448)
Antigène
Voir toutes RIPK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Fonction
- RIPK3 Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this RIPK3 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the RIPK3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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Autre désignation
- RIPK3
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Sujet
- The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
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UniProt
- Q9Y572
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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