RUNX2 anticorps (AA 445-474)

N° du produit ABIN3032500

Cet anticorps Lapin Polyclonal détecte spécifiquement RUNX2 dans WB, ELISA, IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RUNX2 anticorps (AA 445-474) (ABIN3032500)

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-RUNX2 anticorps

Épitope: AA 445-474

Fonction: RUNX2 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 445-474 from the human protein was used as the immunogen for this RUNX2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RUNX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RUNX2

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Autre désignation: RUNX2

Sujet: RUNX2 is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. [UniProt]

UniProt: Q13950