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SIRT6 anticorps (AA 276-305)

SIRT6 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032596
  • Antigène Voir toutes SIRT6 Anticorps
    SIRT6 (Sirtuin 6 (SIRT6))
    Épitope
    • 16
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 276-305
    Reactivité
    • 90
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 86
    • 12
    • 2
    Lapin
    Clonalité
    • 82
    • 18
    Polyclonal
    Conjugué
    • 51
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIRT6 est non-conjugé
    Application
    • 81
    • 39
    • 35
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 276-305 from the human protein was used as the immunogen for this SIRT6 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SIRT6 Anticorps primaire
  • Indications d'application
    Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the SIRT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    SIRT6 (Sirtuin 6 (SIRT6))
    Autre désignation
    SIRT6 (SIRT6 Produits)
    Synonymes
    anticorps 2810449N18Rik, anticorps AI043036, anticorps Sir2l6, anticorps SIR2L6, anticorps zgc:86729, anticorps sirtuin 6, anticorps sirtuin 6 S homeolog, anticorps Sirt6, anticorps SIRT6, anticorps sirt6.S, anticorps sirt6
    Sujet
    NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity).
    UniProt
    Q8N6T7
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