SOCS6 anticorps (AA 40-69)
Aperçu rapide pour SOCS6 anticorps (AA 40-69) (ABIN3029048)
Antigène
Voir toutes SOCS6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-69
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Fonction
- SOCS6 Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 40-69 from the human protein was used as the immunogen for this SOCS6 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the SOCS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the SOCS6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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Autre désignation
- SOCS6
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Sujet
- The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
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UniProt
- O14544
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Pathways
- Signalistation JAK/STAT, Carbohydrate Homeostasis
Antigène
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