SOCS7 anticorps (AA 458-486)

N° du produit ABIN3029049

Cet anticorps anti-SOCS7 est un anticorps Lapin Polyclonal détectant SOCS7 dans ELISA et WB. Adapté pour Humain.

Aperçu rapide pour SOCS7 anticorps (AA 458-486) (ABIN3029049)

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS7 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-SOCS7 anticorps

Épitope: AA 458-486

Réactivité croisée (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 458-486 from the human protein was used as the immunogen for this SOCS7 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SOCS7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOCS7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOCS7

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Autre désignation: SOCS7

Sujet: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

UniProt: O14512