SOX2 anticorps (N-Term)

N° du produit ABIN3032729

L’anticorps Lapin Polyclonal anti-SOX2 a été validé pour WB et ELISA. Il convient pour détecter SOX2 dans des échantillons de Humain.

Aperçu rapide pour SOX2 anticorps (N-Term) (ABIN3032729)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SOX2 anticorps

Épitope: N-Term

Purification: Antigen affinity purified

Immunogène: This SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 30-63 amino acids from the N-terminal region of human SOX2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis