SOX7 anticorps (AA 224-258)
Aperçu rapide pour SOX7 anticorps (AA 224-258) (ABIN3032741)
Antigène
Voir toutes SOX7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 224-258
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 224-258 of the human protein was used as the immunogen for the SOX7 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))
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Autre désignation
- SOX7
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Sujet
- Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
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UniProt
- Q9BT81
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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