NCOA1 anticorps (AA 594-625)

N° du produit ABIN3032055

Cet anticorps anti-NCOA1 Polyclonal Lapin (ABIN3032055) détecte spécifiquement NCOA1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NCOA1 anticorps (AA 594-625) (ABIN3032055)

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NCOA1 anticorps

Épitope: AA 594-625

Fonction: SRC-1 Antibody

Purification: Purified

Immunogène: A portion of amino acids 594-625 from the human protein was used as the immunogen for this SRC-1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SRC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SRC-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NCOA1

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Autre désignation: SRC-1

Sujet: Nuclear receptor coactivator 1/SRC-1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha