tau anticorps (AA 677-707)
Aperçu rapide pour tau anticorps (AA 677-707) (ABIN3031796)
Antigène
Voir toutes tau AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 677-707
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat, Bovine
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Purification
- Purified
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Immunogène
- A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the TAU antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- tau (tau Protein)
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Autre désignation
- tau
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Sujet
- TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]
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UniProt
- P10636
Antigène
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