TLR7 anticorps (AA 899-926)
Aperçu rapide pour TLR7 anticorps (AA 899-926) (ABIN3029177)
Antigène
Voir toutes TLR7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 899-926
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Fonction
- TLR7 Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 899-926 from the human protein was used as the immunogen for this TLR7 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the TLR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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Autre désignation
- TLR7
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Sujet
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
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UniProt
- Q9NYK1
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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