TLR8 anticorps (AA 957-987)

N° du produit ABIN3029181

Détail du produit anti-TLR8 anticorps

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Épitope: AA 957-987

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 957-987 from the mouse protein was used as the immunogen for this TLR8 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TLR8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8 (TLR8 Produits)

Synonymes: anticorps CD288, anticorps toll like receptor 8, anticorps toll-like receptor 8, anticorps TLR8, anticorps Tlr8

Sujet: TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

UniProt: P58682

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades