TOR2A anticorps (AA 194-221)

N° du produit ABIN3029188

Détail du produit anti-TOR2A anticorps

Antigène: TOR2A (Torsin Family 2, Member A (TOR2A))

Épitope: AA 194-221

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOR2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 194-221 from the human protein was used as the immunogen for this TOR2A antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TOR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TOR2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TOR2A

Antigène: TOR2A (Torsin Family 2, Member A (TOR2A))

Autre désignation: TOR2A (TOR2A Produits)

Synonymes: anticorps tor2a, anticorps TOR2A, anticorps zgc:114110, anticorps TORP1, anticorps Prosalusin, anticorps Torsin-2A, anticorps torsin family 2 member A, anticorps torsin family 2, member A L homeolog, anticorps torsin family 2, member A, anticorps TOR2A, anticorps tor2a.L, anticorps tor2a, anticorps Tor2a

Sujet: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

UniProt: Q5JU69