TSG101 anticorps (AA 340-370)
Aperçu rapide pour TSG101 anticorps (AA 340-370) (ABIN3029403)
Antigène
Voir toutes TSG101 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 340-370
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Purified
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Immunogène
- A portion of amino acids 340-370 from the human protein was used as the immunogen for this TSG101 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Autre désignation
- TSG101
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Sujet
- TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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UniProt
- Q99816
Antigène
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