TSG101 anticorps (AA 1-30)
Aperçu rapide pour TSG101 anticorps (AA 1-30) (ABIN3029402)
Antigène
Voir toutes TSG101 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Purification
- Purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this TSG101 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Autre désignation
- TSG101
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Sujet
- TSG101 is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. [UniProt]
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UniProt
- Q99816
Antigène
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