NKX2-1 anticorps (AA 2-1)

N° du produit ABIN3029203

Cet anticorps Lapin Polyclonal détecte spécifiquement NKX2-1 dans WB, FACS et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour NKX2-1 anticorps (AA 2-1) (ABIN3029203)

Antigène: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX2-1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Détail du produit anti-NKX2-1 anticorps

Épitope: AA 2-1

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 2-1 from the human protein was used as the immunogen for this TTF1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TTF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TTF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NKX2-1

Antigène: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Autre désignation: NKX2.1 (TTF1)

Sujet: This gene encodes a protein initially identified as a thyroid-specific transcription factor. NKX2.1/TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P43699

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour