TXNIP anticorps (AA 116-145)

N° du produit ABIN3029123

L’anticorps Lapin Polyclonal anti-TXNIP a été validé pour WB et ELISA. Il convient pour détecter TXNIP dans des échantillons de Souris.

Aperçu rapide pour TXNIP anticorps (AA 116-145) (ABIN3029123)

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNIP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TXNIP anticorps

Épitope: AA 116-145

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 116-145 from the mouse protein was used as the immunogen for this Txnip antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Txnip antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Txnip antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TXNIP

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: Txnip

Sujet: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. [UniProt]

UniProt: Q8BG60

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome