IL23 anticorps (AA 33-67)
Aperçu rapide pour IL23 anticorps (AA 33-67) (ABIN4955879)
Antigène
Voir toutes IL23 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 33-67
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Réactivité croisée (Details)
- Expected species reactivity: Human
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Purification
- Antigen affinity
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Immunogène
- Amino acids 33-67 from the human protein were used as the immunogen for this IL-23 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the IL-23 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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Restrictions
- For Research Use only
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Buffer
- Antibody in 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the IL-23 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL23 (Interleukin 23 (IL23))
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Autre désignation
- IL-23
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Sujet
- Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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UniProt
- Q9NPF7
Antigène
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