S100A8/A9 Complex (Calprotectin) anticorps
Aperçu rapide pour S100A8/A9 Complex (Calprotectin) anticorps (ABIN4956353)
Antigène
Voir toutes S100A8/A9 Complex (Calprotectin) (S100A8/A9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Purification
- purified
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Immunogène
- human recombinant protein
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Isotype
- IgG2b
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Indications d'application
- Dilution: WB 1:1000
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 1 mL deionized water
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Buffer
- PBS, pH 7.23
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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Autre désignation
- calprotectin- S100A8/A9 complex
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Sujet
- Calprotectin is a functional heterocomplex of small EF hand calcium-binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via it's binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammatory conditions.
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Poids moléculaire
- 45 kDa
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Pathways
- S100 Proteins
Antigène
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