HNRNPC anticorps (N-Term)
Aperçu rapide pour HNRNPC anticorps (N-Term) (ABIN497942)
Antigène
Voir toutes HNRNPC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-142, N-Term
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Specificité
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Recognizes hnRNP-C1/C2/HNRNPC (1-152).
Cellular Localization: Nucleus. -
Réactivité croisée (Details)
- Species reactivity (expected):Mouse (100 %), Rat (100 %), Bovine (100 %) and Rabbit (92 %)Species reactivity (tested):Human.
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Purification
- Antigen-Affinity Chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 142 of hnRNP-C1/C2.
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Indications d'application
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Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/100-1/250. Positive Controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.79 mg/mL
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Buffer
- 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody undiluted (in aliquots) at -20 °C.
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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Autre désignation
- HnRNP-C1/C2 / HNRNPC
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Sujet
- HnRNP-C1/C2 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.Synonyms: HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1 / hnRNP C2
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ID gène
- 3183, 9606
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UniProt
- P07910
Antigène
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