TTC8 anticorps (Internal Region)

N° du produit ABIN498031

Détail du produit anti-TTC8 anticorps

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Épitope: Internal Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-KEVLKQDNTH VE

Specificité: This antibody is expected to recognize all reported isoforms (NP_653197.2, NP_938051.1, NP_938052.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine and Porcine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the Internal region of the protein sequence according to NP_653197.2, NP_938051.1, NP_938052.1.

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.2-0.6 μg/mL. Approx 60 kDa band observed in Human Testis lysates(calculated MW of 58.0 kDa according to NP_653197.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TTC8

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Autre désignation: TTC8 / BBS8 (TTC8 Produits)

Synonymes: anticorps TTC8, anticorps bbs8, anticorps fk26c02, anticorps wu:fk26c02, anticorps zgc:136718, anticorps DKFZp459L2429, anticorps BBS8, anticorps RP51, anticorps 0610012F22Rik, anticorps AV001447, anticorps tetratricopeptide repeat domain 8, anticorps TTC8, anticorps ttc8, anticorps lpa_01174, anticorps Ttc8

Sujet: Defects in TTC8 are the cause of Bardet-Biedl syndrome type 8 (BBS8). This is a genetically heterogeneous, autosomal recessive disorder and the primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.Synonyms: Bardet-Biedl syndrome 8 protein, TPR repeat protein 8, Tetratricopeptide repeat protein 8

ID gène: 123016

NCBI Accession: NP_653197

UniProt: Q8TAM2

Pathways: Signalisation Hedgehog