IL9 Receptor anticorps

N° du produit ABIN498148

Cet anticorps Lapin Polyclonal détecte spécifiquement IL9 Receptor dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL9 Receptor anticorps (ABIN498148)

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL9 Receptor est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL9 Receptor anticorps

Specificité: This antibody detects endogenous levels of IL-9R protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur IL9 Receptor

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Autre désignation: CD129 / IL9R

Sujet: Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53 % amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.Synonyms: IL-9 receptor, IL-9R, Interleukin-9 receptor

ID gène: 3581

NCBI Accession: NP_002177

UniProt: Q01113

Pathways: Signalistation JAK/STAT, Growth Factor Binding