beta 2 Adrenergic Receptor anticorps

N° du produit ABIN498188

Détail du produit anti-beta 2 Adrenergic Receptor anticorps

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta 2 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of AR-β2 protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-beta 2 Adrenergic Receptor (ABIN498188)

Müller, Schwab, Rosenfeld, Antonow-Schlorke, Nathanielsz, Rakers, Schubert, Witte, Rupprecht: "Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation." dans: Journal of vascular research, Vol. 54, Issue 5, pp. 259-271, (2017) (PubMed).

Détails sur beta 2 Adrenergic Receptor

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Autre désignation: beta-2 Adrenergic Receptor (ADRB2 Produits)

Synonymes: anticorps zgc:162188, anticorps adrb2, anticorps Adrb-2, anticorps Badm, anticorps Gpcr7, anticorps ADRB2R, anticorps ADRBR, anticorps B2AR, anticorps BAR, anticorps BETA2AR, anticorps adrenoceptor beta 2, anticorps adrenoceptor beta 2, surface b, anticorps beta2-adrenergic receptor, anticorps adrenergic receptor, beta 2, anticorps ADRB2, anticorps adrb2b, anticorps LOC100136153, anticorps Adrb2

Sujet: Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthm,a obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor

Poids moléculaire: approx. 47 kDa

ID gène: 154

NCBI Accession: NP_000015

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation