FLT3LG anticorps

N° du produit ABIN498318

Cet anticorps anti-FLT3LG Polyclonal Lapin (ABIN498318) détecte spécifiquement FLT3LG dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FLT3LG anticorps (ABIN498318)

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT3LG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FLT3LG anticorps

Specificité: This antibody detects endogenous levels of Flt3-L protein. (region surrounding His206)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FLT3LG

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Autre désignation: Flt3 Ligand

Sujet: Flt 3 ligand (Flt 3-L), variously designated Flt 3/Flk 2 ligand or FL, is a 17 kDa hematopoietic growth factor that stimulates the proliferation of stem and CD34+ progenitor cells and has been cloned from both mouse and human genomes. Flt 3-L is a potent in vitro growth stimulator of granulocytemacrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and G-CSF-dependent granulocyte-macrophage committed precursors from Lin CD34+ bone marrow cells as well as other primitive B cell populations. Additionally, Flt 3-L stimulates the proliferation of hematopoietic progenitor cells isolated from mouse fetal liver or adult mouse bone marrow. Flt 3-L does not, however, affect the growth of erythroid-committed progenitors. A Flt-3 ligand exists in two forms and is active as both a soluble and as a membrane-bound ligand. The Flt 3-L receptor, Flt 3, is a tyrosine kinase expressed on CD34+ cells that shares a high degree of homology with the SCF (stem cell factor) receptor, c-Kit and c-Fms.Synonyms: FLT3LG, Flt3L, SL cytokine, fms-related tyrosine kinase 3 ligand

Poids moléculaire: approx. 26 kDa

ID gène: 2323

NCBI Accession: NP_001450

UniProt: P49771

Pathways: Signalisation RTK