Serotonin Receptor 1E anticorps

N° du produit ABIN498367

Cet anticorps Lapin Polyclonal détecte spécifiquement Serotonin Receptor 1E dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Serotonin Receptor 1E anticorps (ABIN498367)

Antigène: Serotonin Receptor 1E (HTR1E)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1E est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Serotonin Receptor 1E anticorps

Specificité: This antibody detects endogenous levels of SR-1E protein. (region surrounding Ala127)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Serotonin Receptor 1E

Antigène: Serotonin Receptor 1E (HTR1E)

Sujet: The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.Synonyms: 5-HT-1E, 5-HT1E, 5-hydroxytryptamine receptor 1E

Poids moléculaire: approx. 42 kDa

ID gène: 3354

NCBI Accession: NP_000856

UniProt: P28566

Pathways: Signalistation JAK/STAT, cAMP Metabolic Process