Serotonin Receptor 3A anticorps

N° du produit ABIN498369

Cet anticorps anti-Serotonin Receptor 3A Polyclonal Lapin (ABIN498369) détecte spécifiquement Serotonin Receptor 3A dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Serotonin Receptor 3A anticorps (ABIN498369)

Antigène: Serotonin Receptor 3A (HTR3A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 3A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Serotonin Receptor 3A anticorps

Specificité: This antibody detects endogenous levels of SR-3A protein. (region surrounding Trp190)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Serotonin Receptor 3A

Antigène: Serotonin Receptor 3A (HTR3A)

Sujet: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

Poids moléculaire: approx. 55 kDa

ID gène: 3359

NCBI Accession: NP_000860

UniProt: P46098

Pathways: Synaptic Membrane