CDC7 anticorps

N° du produit ABIN498406

Détail du produit anti-CDC7 anticorps

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Cdc7 protein. (region surrounding Phe35)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CDC7

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Autre désignation: CDC7 (CDC7 Produits)

Synonymes: anticorps CDC7L1, anticorps HsCDC7, anticorps Hsk1, anticorps huCDC7, anticorps AI597260, anticorps Cdc7l1, anticorps muCdc7, anticorps cell division cycle 7, anticorps cell division cycle 7-related protein kinase, anticorps cell division cycle 7 (S. cerevisiae), anticorps CDC7, anticorps Tsp_08585, anticorps Cdc7

Sujet: DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.Synonyms: CDC7-related kinase, CDC7L1, Cell division cycle 7-related protein kinase, HsCdc7, huCdc7

Poids moléculaire: approx. 70 kDa

ID gène: 8317

NCBI Accession: NP_001127891

UniProt: O00311

Pathways: Mitotic G1-G1/S Phases, DNA Replication