DGKQ anticorps
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- Antigène Voir toutes DGKQ Anticorps
- DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DGKQ est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody reacts to DGKQ.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product DGKQ Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
- Autre désignation
- DAG Kinase theta (DGKQ Produits)
- Synonymes
- anticorps DAGK, anticorps DAGK4, anticorps DAGK7, anticorps 110kDa, anticorps Dagk4, anticorps Dgkd, anticorps diacylglycerol kinase theta, anticorps diacylglycerol kinase, theta, anticorps diacylglycerol kinase, theta, putative, anticorps DGKQ, anticorps Dgkq, anticorps Smp_163080, anticorps Tsp_13406
- Sujet
- Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.Synonyms: DAGK4, DGK-theta, DGKQ, Diacylglycerol kinase theta, Diglyceride kinase theta
- Poids moléculaire
- approx. 101 kDa
- ID gène
- 1609
- NCBI Accession
- NP_001338
- UniProt
- P52824
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